Science Angel Syndicate invests in Halo Therapeutics who raised £1.5m to bring first antiviral spray into clinic

Investors in this round: Science Angel Syndicate, Development Bank of Wales, KBA Group

Clinical trials of an easy-to-use home therapeutic treatment for SARS-CoV-2 (coronaviruses) are underway following a £1.5 million investment led by the Development Bank of Wales alongside Science Angel Syndicate (SAS) members and the KBA Group.

Based on world-class research carried out at Bristol University, Halo Therapeutics was established as a spin-out company in 2020 by CEO Dr Daniel Fitzgerald, Professor Christiane Schaffitzel, and Professor Imre Berger. Halo Therapeutics has been attracted to Wales following an £1,000,000 equity investment by the Development Bank of Wales.

This first-in-human study of Halo Therapeutic’s respiratory antiviral spray for coronaviruses will investigate the safety and tolerability of the treatment prior to subsequent studies being conducted in patients that are SARS-CoV-2 positive or are at risk of becoming SARS-CoV-2 positive.

Professor Berger added: “Vaccination and treatments have reduced the impact of the virus but it is still a significant health risk. Our self-administered and cost-effective antiviral treatment stops the virus from entering and multiplying in the nasal epithelial cells, where it can then spread to the throat and then into the lungs. It is a potential game-changer in the treatment and prevention of coronaviruses, particularly with the emergence of new viruses.

Dr Mark Bowman, Venture Fund Manager for the Development Bank, commented: “It is encouraging to see a growing number of life sciences and medical technology companies investing in Wales. As a nation, we offer a vibrant and prosperous environment that is an attractive proposition for early-stage businesses like Halo Therapeutics as they move towards global commercialisation from a base here in Wales.”

Integrated healthcare Physician Dr Nikolaos Kostopoulos, co-lead of the KBA Group, added: “Due to a large portion of the unvaccinated, and the waning efficacy of the vaccines, we still see a high incidence and morbidity of Covid infections, as well as a growing number of long Covid patients. HALO’s antiviral spray will be the best prevention against being infected by new mutant strains, which continue to spread globally. We need to be better prepared for the next waves of Covid this time.”

Dr Johnathan Matlock, Co-Founder of SAS said: "We have worked closely with Imre and Daniel since their pre-seed round. We are delighted to have helped them to secure this latest funding round from the Development Bank of Wales. Beginning with publications in the world’s leading scientific journals it is rare that you get the opportunity to see scientific innovations so rapidly translate into the clinic and one step closer to patients.”

*Risk disclaimer: Investment in early-stage companies involves risks such as illiquidity, lack of dividends, loss of investment and dilution. For professional investors only.

Public relations enquiries

Dr Johnathan Matlock, Director



ABOUT HALO Therapeutics

HALO’s vision is to roll out a class of small molecule pan-coronavirus therapeutics targeting the central axis of disease pathology: lipid regulation. The company is located in the Welsh ICE, Caerphilly.

CONTACT: Daniel Fitzgerald email: df@halo-therapeutics.com website: www.halo-therapeutics.com


The Development Bank of Wales is a Welsh development bank that provides financial support for Welsh businesses and is owned by the Welsh Government. The bank provides loans for businesses to start up, strengthen and grow and also provides equity investments for already established businesses.

CONTACT: Mark Bowman email: mark.bowman@developmentbankwales.com


The KBA Group is an angel consortium of high net worth individuals co-led by Dr Nikolaos Kostopoulos and Paras Barot.

CONTACT: Paras Barot email: parasbarot@hotmail.com

ABOUT Science Angel Syndicate

Science Angel Syndicate was founded in 2021 with a mission to source world-class scientific discoveries, provide unique scientific due diligence and help our members to identify exceptional investment opportunities that tackle the most important global challenges. Our collective knowledge helps our members invest in the most exciting companies of tomorrow, founded by leading scientists at the forefront of their fields.

Learn more about Science Angel Syndicate: www.scienceangelsyndicate.com


Science Angel Syndicate invests in Halo Therapeutics who raised £1.5m to bring first antiviral spray into clinic

Science Angel Syndicate invests in Halo Therapeutics who raised £1.5m to bring first antiviral spray into clinic

By ScienceAngelSyndicate Empirical Ventures Profile 22 May 2023