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CTEye secures pre-seed funding from the Royal College of Art’s Design & Innovation Fund to combat neurodegenerative disease with smart mouthguard technology

The Royal College of Art (RCA) and Infinity Asset Management LLP are delighted to announce that the RCA Design & Innovation S/EIS Fund has completed a pre-seed investment in CTEye, a sports technology startup advancing the standards of brain health monitoring in contact sports

Founded by Georgios Koukoulis, CTEye addresses a critical gap in athlete safety: the cumulative effect of head impacts. While traditional solutions often focus on binary “yes/no” concussion detection, CTEye is developing a smart mouthguard embedded with advanced sensors to provide a continuous, long-term perspective on brain health.

CTEye’s smart mouthguard, Byte, captures real time impact data including force, direction, and frequency, which is analysed through the companion mobile app. The CTEye app transforms this biomechanical data into actionable metrics designed to support athletes, coaches, and clinicians in brain injury management, recovery monitoring, and return to play decision making.

Alongside impact tracking, CTEye combines periodic neurocognitive and motor assessments delivered through engaging, game based challenges, enabling continuous monitoring of athlete condition while maintaining high athlete compliance and consistent longitudinal data collection.

The funding will accelerate the development of the Byte device and its software ecosystem, with several pilot programs involving professional athletes already under way.

“Securing this pre-seed funding from the RCA is a significant milestone for CTEye. It validates our mission to move the conversation beyond simply detecting concussions to proactively preserving long-term brain health and allows us to accelerate the development of our sensor technology and 3D mapping software.” Georgios Koukoulis, Founder of CTEye

“We’re thrilled to welcome CTEye to our portfolio. Georgios has identified a profound problem in contact sports, the invisible, cumulative damage to the brain, and addressed it with a solution that blends rigorous biomechanics with user-centric design.”
Thomas Pedrick, Investment Manager at InnovationRCA